The enzymeA protein that speeds up the process of chemical reactions in the body without becoming altered in the process. Almost every biological process is driven by the activity of enzymes. Without enzyme catalysts, the complex reactions that build and break down cell parts would not happen at a rate compatible with life. Enzyme names usually describe the reaction that is being catalyzed and all of them end in -ase. Rad18, with the help of the Cdc7 proteinOne of the four basic types of biomolecule. Proteins are polymers made up of strings of amino acids. Proteins serve many functions in organisms including transport of molecules, structure, cell adhesion and as signaling molecules such as hormones. Many transcription factors, including p53 and Rb are proteins., directs DNAAbbreviation for deoxyribonucleic acid. Composed of very long strings of nucleotides, which are abbreviated as A, C, G and T. DNA is the storage form of our genetic material. All of the instructions for the production of proteins are encoded in our DNA. repair machinery to sites of DNA damage. DNA repair is important in healthy cells but this repair can interfere with certain forms of cancer treatment. If cellular DNA is severely damaged, the cell will often die instead of being repaired. Many chemotherapyTreatment of cancer patients with anticancer drugs. Commonly called 'chemo'. These drugs work by attacking cell growth or division. Often these agents are used in combination to take advantage of their different modes of attack on cell division. drugs use platinum-based drugs to purposely cause damage and thus jumpstart cancer cell death. Many cancers, however, have high levels of Cdc7, which allows them to counteract the effects of the drugs and can lead to drug resistance. Cdc7 offers a promising new target for treating cancers resistant to platinum-based therapy.
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