
Cancer cells that spread (metastasizeThe movement of a cancer to a location outside its site of origin. The distant growths are termed metastases.) to other parts of the body from an original location frequently travel through the bloodstream. Because there are so few of these cells in blood, compared to the enormous number of red and white blood cells, the circulating tumor cells (CTC) are very difficult to find. A test that could find CTC would make diagnosing cancer easier and help doctors to design treatment plans.
New research has shown that it is possible to create small sheets coated with tiny 'nano dots'. Researchers then attached antibodiesAntibodies are proteins produced by a type of white blood cell (B cells or B lymphocytes). Antibodies are able to stick very tightly to specific targets. Antibodies are currently being used as anti-cancer drugs (i.e. Herceptin). to the dots and showed that this new (bumpy and sticky) surface, was very good at capturing CTC. The researchers hope to develop a laboratory test to detect CTC with their technology.