Allopurinol

Imagen de Allopurinol
Brand name: Zyloprim
Brand name: Lopurin
Brand name: Aloprim
IUPAC: 1,5-Dihydro-4H-pyrazolo[3,4-d ]pyrimidin-4-one
FDA approval: Yes
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Usage:

Allopurinol is used in treatment of gout, high levels of acidity and prevention of gout attacks, which can be a side effects of certain cancer medications. Prescribed as an oral tablet, Allopurinol is taken once or twice a day after a meal.1  

  • 1Allopurinol MedlinePlus https://medlineplus.gov/druginfo/meds/a682673.html
Mechanism:

Described as a xanthine oxidase inhibitor, Allopurinol promotes the reduction of uric acid in the body.1

 

The structure below shows the 3D conformer Allopurinol. 

  • 1Allopurinol MedlinePlus https://medlineplus.gov/druginfo/meds/a682673.html
Side effects:

Allopurinol can increase the number of gout attacks suffered in the initial months of its use.  Other side effects could include: upset stomach, diarrhea and drowsiness.1

  • 1Allopurinol MedlinePlus https://medlineplus.gov/druginfo/meds/a682673.html