Theodor Boveri proposes the Somatic MutationA mutation that occurs in a typical body cell such as those that make up our skin or organs. These mutations are not transmitted to offspring. Somatic mutations can be contrasted with germ line mutations that occur in the cells destined to become our gametes, sperm or egg. Mutations in germ cells may be transmitted to offspring. Hereditary forms of cancer are passed to the offspring via gametes and sporadic forms of cancer arise via somatic mutations. It is possible that the same cancer type can arise in either way. Theory of Cancer. He believed that cancer was caused by abnormal chromosomes.
Boveri was on to something when he proposed this theory. It is now known that many things lead to the development of cancer, but genetic instability is at the root of cancer.1
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