A review of patients enrolled in 16 clinical trials has revealed that the anti-angiogenesis drug bevacizumab (Avastin®) may actually increase the risk of death when combined with certain chemotherapy drugs. In combination with taxanes or platinum containing drugs, bevacizumab was associated with a significantly higher risk of death from treatment side-effects. The results indicate that the drug may have to be used with caution or not at all with these types of chemotherapy agents.
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