
Many cases of stomach (gastric) cancer are caused by long-term infection with the bacterium Helicobacter pylori. A vaccine that prevents infection with H. pylori could reduce the incidence of gastric cancer. U.S. researchers, using computer modeling, have developed a vaccine that generates a strong immune response against the bacteriaA microscopic organism. Bacteria lack a nucleus. They are found in very large numbers in almost all locations, including the human body. While most bacteria are harmless or necessary, some can cause disease and death. and reduces stomach colonization. The vaccine did not greatly impact the changes in gastric tissue caused by infection. Additional work is needed to create a vaccine with the desired impact on cancer development.