Exemestane

Exemestane (Aromasin®) binds irreversibly (permanently) to the aromatase enzymeA protein that speeds up the process of chemical reactions in the body without becoming altered in the process. Almost every biological process is driven by the activity of enzymes. Without enzyme catalysts, the complex reactions that build and break down cell parts would not happen at a rate compatible with life. Enzyme names usually describe the reaction that is being catalyzed and all of them end in -ase.. This stops aromatase from making estrogenA steroid sex hormone. Estrogen's structure is closely related to cholesterol. Produced by the ovaries, estrogen has effects on the reproductive, cardiovascular and skeletal systems. Estrogen is also a growth factor for some types of cells, including breast cells. Inhibitors of estrogen function such as tamoxifen and arimidex are used to block the growth effects of estrogen. See also, estrogen receptor. by stopping the conversion of adrenal androgens, which prevents the growth of estrogen dependent cancer.1

The structure below shows the breast cancer drug Aromasin, also known as Exemestane.