Brigatinib

Brigatinib is an oral prescription used in the treatment of non-small cell lung cancer. It is often combined with other types of cancer therapy, which produces quality results.1
Brigatinib is a small molecule targeted cancer therapy used in the treatment of non-small cell lung cancer. Brigatinib has exhibited activity as a strong inhibitor of anaplastic lymphomaA cancer arising in the lymphatic system. The white blood cells affected are part of the body's immune system. The lymphatic system is a large network of vessels that carry fluid and cells of the immune system around the body. Lymph nodes are regional collection centers in the lymphatic system. See also, 'lymphatic system'. kinaseAn enzyme that adds phosphate groups to another molecule. Many key proteins controlling gene expression are kinase targets. Addition of a phosphate group to a protein can alter the activity of the protein and are often used as molecular on/off switches. For example, the retinoblastoma tumor suppressor gene is 'off' when phosphate groups are added to the protein at specific locations. Removal of the phosphate groups turns the protein 'on'. Enzymes that remove phosphate groups are known as phosphatases. Note that all enzymes, regardless of function, end in ASE (ALK) (cancerous cell proteins) and epidermal growth factorA substance that stimulates cell division. Growth factors are usually small proteins or steroid hormones. They may be secreted by the same cells on which they act or by cells that reside in a different part of the body than the target cells. Some examples of growth factors include estrogen, a growth factor for breast cells, and VEGF, a growth factor that causes the development of blood vessels. Several different anti-cancer treatments are designed to inhibit the activity of growth factors. receptor (EGFR), which in turn leads to decrease in cancerous cells and overall apoptosisAlso called programmed cell death. Apoptosis is a natural process that occurs throughout the lives of almost all animals and plants. The death of the cells is a carefully controlled process that does not generate any inflammation..1
The most serious side effects of brigatinib include: swelling of the lungs (if extremely severe seek medical attention), high blood pressure, slow heart rate, vision problems and tenderness/weakness. However, the most common side effects include: nausea, diarrhea, stomach problems and headache.1
Patients with prior lung or breathing problems should alert their physician before starting a Brigatinib prescription. Women who are pregnant or are looking to become pregnant should be especially careful in taking Brigatinib.1
- 1.a. b. c. Patient Information. (n.d.). Retrieved July 19, 2017, from https://www.alunbrig.com/
- 2. Health Care Professionals Information. (n.d.). Retrieved July 19, 2017, from https://www.alunbrig.com/hcp?utm_source=google&utm_medium=cpc&utm_term=brigatinib%2Bmechanism%2Bof%2Baction&utm_campaign=GS%2B-%2BNA%2B-%2BBR%2B-%2BGeneric%2B-%2BHCP_GS%2B-%2BInformation_EX