Ramucirumab
Cyramza is injected into a vein through an IV. A healthcare provider will give you this injection. You may be given medication to prevent certain side effects while you are receiving Cyramza. Cyramza is sometimes given once every 2 weeks. It may also be given in a 21-day treatment cycle and you may only need to use the medicine during the first day of each cycle. Follow your doctor's dosing instructions very carefully. While using Cyramza, you may need frequent blood or urine tests. Your blood pressure will need to be checked often. If you need surgery, tell the surgeon ahead of time that you are using Cyramza. You may need to stop using the medicine for a short time.
CYRAMZA™ is a monoclonalDerived from a single source. In the context of cancer, the term is used in two ways: 1) to refer to the fact that tumors arise from a single damaged cell and 2) to describe the antibodies used in the treatment of cancer. antibodyAntibody molecules tightly bind to their targets (usually proteins) with great specificity. Antibody binding alerts the immune system to target the bound molecule for destruction. Specific antibodies can be made in the laboratory. , Vascular Endothelial Growth FactorA substance that stimulates cell division. Growth factors are usually small proteins or steroid hormones. They may be secreted by the same cells on which they act or by cells that reside in a different part of the body than the target cells. Some examples of growth factors include estrogen, a growth factor for breast cells, and VEGF, a growth factor that causes the development of blood vessels. Several different anti-cancer treatments are designed to inhibit the activity of growth factors. Receptor 2 (VEGFR2) Inhibitor. Cyramza works by blocking the blood supply that fuels tumor growth. The drug is intended for patients whose tumor has grown during or following treatment with platinum-based chemotherapyTreatment of cancer patients with anticancer drugs. Commonly called 'chemo'. These drugs work by attacking cell growth or division. Often these agents are used in combination to take advantage of their different modes of attack on cell division., and it is to be used in combination with docetaxel, another type of chemotherapy.
Common Cyramza side effects may include: feeling weak or tired; diarrhea; nosebleeds; low white blood cell counts; or high blood pressure.
Get emergency medical help if you have signs of an allergic reaction to Cyramza: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your caregiver right away if you feel light-headed, chilled, sweaty, or have chest pain, chest tightness, back pain, trouble breathing, or numbness and tingling. Cyramza can increase your risk of serious bleeding.
Call your doctor at once if you have: any wound that will not heal; headache, confusion, change in mental status, vision loss, seizure (convulsions); severe or ongoing stomach pain, vomiting, or diarrhea; a light-headed feeling, like you might pass out; low white blood cell counts - fever, swollen gums, painful mouth sores, pain when swallowing, skin sores, cold or flu symptoms, cough, trouble breathing; dangerously high blood pressure - severe headache, blurred vision, buzzing in your ears, anxiety, shortness of breath, uneven heartbeats; kidney problems - puffy eyes, swelling in your ankles or feet, weight gain, urine that looks foamy; signs of stomach bleeding - severe stomach pain, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; symptoms of a blood clot - sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance; or heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating.
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