Department of Leukemia
The University of Texas M.D. Anderson Cancer Center
Dr. Issa's research focuses on the epigenetics of cancer. The term epigenetics refers to events that can change how a gene functions without changing the DNA sequence of the gene. The changes can be slight chemical modifications to the DNA itself or modifications to the the proteins in which the DNA is packaged. In this interview, Dr. Issa explains epigenetics and the way that epigenetic changes can influence cancer development. Epigenetic changes are also an important target for potential cancer drugs.
Interview Questions
About Jean-Pierre Issa
(Time:
0min
19sec
)
How Dr. Issa Became Interested in Medical Oncology
(Time:
1min
50sec
)
Understanding Epigenetics
(Time:
3min
30sec
)
DNA Methylation and How it Affects Gene Expression
(Time:
4min
32sec
)
The Importance of Epigenetics in the Origin of Cancer
(Time:
4min
41sec
)
Parental Influence on Epigenetics Though Their Behavior
(Time:
2min
31sec
)
Factors That Affect Epigenetics
(Time:
2min
58sec
)
Epigenetics and Drug Research
(Time:
2min
14sec
)
Dr. Issa's Current Research
(Time:
1min
32sec
)
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